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Adoptive immunotherapy of cancer using monocyte-derived macrophages: rationale, current status, and perspectives

Andreesen, Reinhard and Hennemann, B. and Krause, S. W. (1998) Adoptive immunotherapy of cancer using monocyte-derived macrophages: rationale, current status, and perspectives. Journal of leukocyte biology 64 (4), pp. 419-26.

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Abstract

Adoptive transfer of host defense cells may be able to correct an otherwise defective generation of competent immune cells in patients with cancer. Ex vivo-grown cytotoxic macrophages (MAC) able to recognize and destroy tumor cells but not normal cells are effective in murine models of metastasizing tumors. After the development of large-scale technology to generate MAC in vitro from blood ...

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Item Type:Article
Date:1998
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
9766621PubMed ID
Classification:
NotationType
AnimalsMESH
Cell TransplantationMESH
Clinical Trials as TopicMESH
Dendritic Cells/immunologyMESH
HumansMESH
Immunotherapy, AdoptiveMESH
Interferon-gamma/therapeutic useMESH
Lipopolysaccharides/pharmacologyMESH
Macrophages/immunologyMESH
Models, ImmunologicalMESH
Monocytes/immunologyMESH
Neoplasms/therapyMESH
Transplantation, AutologousMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:35
Last Modified:15 Apr 2010 05:35
Item ID:14326
Owner Only: item control page
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