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Selective depletion of CD14+ CD16+ monocytes by glucocorticoid therapy

Fingerle-Rowson, G. and Angstwurm, M. and Andreesen, Reinhard and Ziegler-Heitbrock, H. W. (1998) Selective depletion of CD14+ CD16+ monocytes by glucocorticoid therapy. Clinical and experimental immunology 112 (3), pp. 501-6.

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Abstract

Glucocorticoids (GC) are potent anti-inflammatory and immunosuppressive agents that act on many cells of the body, including monocytes. Here we show that a 5-day course of high dose GC therapy differentially affected the CD14++ and the CD14+ CD16+ monocyte subpopulations in 10 patients treated for multiple sclerosis. While the classical (CD14++) monocytes exhibited a substantial increase from 495 ...

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Item Type:Article
Date:1998
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
2478233PubMed ID
Classification:
NotationType
AdultMESH
Antigens, CD14/immunologyMESH
FemaleMESH
Flow CytometryMESH
Glucocorticoids/administration & dosageMESH
HumansMESH
ImmunosuppressionMESH
Immunosuppressive Agents/administration & dosageMESH
Injections, IntravenousMESH
MaleMESH
Middle AgedMESH
Monocytes/immunologyMESH
Multiple Sclerosis/immunologyMESH
Receptors, IgG/immunologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:31
Last Modified:15 Apr 2010 05:31
Item ID:14331
Owner Only: item control page
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