Eissner, G. and Kirchner, S. and Lindner, H. and Kolch, W. and Janosch, P. and Grell, M. and Scheurich, P. and Andreesen, Reinhard and Holler, E. (2000) Reverse signaling through transmembrane TNF confers resistance to lipopolysaccharide in human monocytes and macrophages. Journal of immunology (Baltimore, Md. : 1950) 164 (12), pp. 6193-8.
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We have previously reported that the CD14+ monocytic subpopulation of human PBMC induces programmed cell death (apoptosis) in cocultured endothelial cells (EC) when stimulated by bacterial endotoxin (LPS). Apoptosis is mediated by two routes, first via transmembrane TNF-alpha (mTNF) expressed on PBMC and, in addition, by TNF-independent soluble factors that trigger apoptosis in EC. Neutralizing ...
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|Institutions:||Medicine > Abteilung für Hämatologie und Internistische Onkologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||15 Apr 2010 05:23|
|Last Modified:||15 Apr 2010 05:23|