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Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells

Fritsche, Jana and Mondal, Krishna and Ehrnsperger, Achim and Andreesen, Reinhard and Kreutz, Marina (2003) Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells. Blood 102 (9), pp. 3314-6.

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Abstract

25-Hydroxyvitamin D3-1 alpha-hydroxylase (25(OH)D3-1 alpha-hydroxylase), the key enzyme of 1 alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) production, is expressed in monocyte-derived macrophages (MACs). Here we show for the first time constitutive expression of 25(OH)D3-1 alpha-hydroxylase in monocyte-derived dendritic cells (DCs), which was increased after stimulation with lipopolysaccharide ...

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Item Type:Article
Date:2003
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
12855575PubMed ID
10.1182/blood-2002-11-3521DOI
Classification:
NotationType
25-Hydroxyvitamin D3 1-alpha-Hydroxylase/metabolismMESH
Antigens, CD34MESH
Calcitriol/physiologyMESH
Cell DifferentiationMESH
Dendritic Cells/metabolismMESH
HumansMESH
Lipopolysaccharides/pharmacologyMESH
MacrophagesMESH
Monocytes/cytologyMESH
Paracrine CommunicationMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 06:19
Last Modified:20 Apr 2010 06:19
Item ID:14414
Owner Only: item control page
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