Gottfried, Eva and Faust, Stefan and Fritsche, Jana and Kunz-Schughart, Leoni A. and Andreesen, Reinhard and Miyake, Kensuke and Kreutz, Marina (2003) Identification of genes expressed in tumor-associated macrophages. Immunobiology 207 (5), pp. 351-9.
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Most malignant tumors contain so-called tumor-associated macrophages (TAM) as a major component of their leukocytic infiltrate. To investigate the impact of the tumor microenvironment on activation and differentiation of macrophages, we established a 3-dimensional model system by culturing human monocytes within multicellular tumor spheroids. After 7 days, monocyte-derived TAM were isolated and ...
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|Institutions:||Medicine > Abteilung für Hämatologie und Internistische Onkologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||20 Apr 2010 05:50|
|Last Modified:||20 Apr 2010 05:50|