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Survival and tumor localization of adoptively transferred Melan-A-specific T cells in melanoma patients

Meidenbauer, Norbert and Marienhagen, Joerg and Laumer, Monika and Vogl, Sandra and Heymann, Jana and Andreesen, Reinhard and Mackensen, Andreas (2003) Survival and tumor localization of adoptively transferred Melan-A-specific T cells in melanoma patients. Journal of immunology (Baltimore, Md. : 1950) 170 (4), pp. 2161-9.

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Abstract

Adoptive T cell therapy has been successfully used for treatment of viral and malignant diseases. However, little is known about the fate and trafficking of transferred Ag-specific T cells. Using the tetramer (TM) technology which allows for detection and quantification of Ag-specific CTL, we assessed the frequency of circulating Melan-A-specific CTL in advanced melanoma patients during adoptive ...

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Item Type:Article
Date:2003
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
12574389PubMed ID
Classification:
NotationType
Antigens, NeoplasmMESH
Cell Division/immunologyMESH
Cell LineMESH
Cell Movement/immunologyMESH
Cell Survival/immunologyMESH
Epitopes, T-Lymphocyte/immunologyMESH
HumansMESH
ImmunophenotypingMESH
Immunotherapy, Adoptive/methodsMESH
Indium Radioisotopes/metabolismMESH
Infusions, IntravenousMESH
Liver/metabolismMESH
Lung/metabolismMESH
Lymphocyte ActivationMESH
Melanoma/therapyMESH
Neoplasm Proteins/immunologyMESH
Pilot ProjectsMESH
Spleen/metabolismMESH
T-Lymphocytes, Cytotoxic/transplantationMESH
Tumor Cells, CulturedMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 05:49
Last Modified:20 Apr 2010 05:49
Item ID:14417
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