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Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group

Schmoll, H.-J. and Kollmannsberger, C. and Metzner, B. and Hartmann, J. T. and Schleucher, N. and Schöffski, P. and Schleicher, J. and Rick, O. and Beyer, J. and Hossfeld, D. and Kanz, L. and Berdel, W. E. and Andreesen, Reinhard and Bokemeyer, C. (2003) Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 21 (22), pp. 4083-91.

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Abstract

PURPOSE: Patients with disseminated germ cell cancer and poor prognosis (International Germ Cell Cancer Collaborative Group [IGCCCG] classification) achieve only a 45% to 50% long-term survival by standard chemotherapy. First-line high-dose chemotherapy might be able to improve the result. This analysis reports toxicity and long-term results of a large phase I/II study of sequential high-dose ...

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Item Type:Article
Date:2003
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
14568986PubMed ID
10.1200/JCO.2003.09.035DOI
Classification:
NotationType
AdolescentMESH
AdultMESH
Antineoplastic Combined Chemotherapy Protocols/adverse effectsMESH
Cisplatin/adverse effectsMESH
Combined Modality TherapyMESH
Disease-Free SurvivalMESH
Etoposide/adverse effectsMESH
Germinoma/therapyMESH
Hematopoietic Stem Cell TransplantationMESH
HumansMESH
Ifosfamide/adverse effectsMESH
MaleMESH
Middle AgedMESH
PrognosisMESH
Survival RateMESH
Testicular Neoplasms/therapyMESH
Time FactorsMESH
Transplantation, AutologousMESH
Treatment OutcomeMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 05:49
Last Modified:20 Apr 2010 05:49
Item ID:14420
Owner Only: item control page
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