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Antiangiogenetic therapy with pioglitazone, rofecoxib, and metronomic trofosfamide in patients with advanced malignant vascular tumors

Vogt, Thomas and Hafner, Christian and Bross, Klaus and Bataille, Frauke and Jauch, Karl-Walter and Berand, Anna and Landthaler, Michael and Andreesen, Reinhard and Reichle, Albrecht (2003) Antiangiogenetic therapy with pioglitazone, rofecoxib, and metronomic trofosfamide in patients with advanced malignant vascular tumors. Cancer 98 (10), pp. 2251-6.

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Abstract

BACKGROUND: Systemic therapy options for patients with advanced angiosarcomas are limited, and their prognosis is poor. The idea of angiostatic therapy following the paradigm of metronomic dosed chemotherapeutics combined with proapoptotic biomodulators had not been considered previously in these patients. Therefore, in a pilot study, the efficacy of metronomically scheduled, low-dose ...

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Item Type:Article
Date:2003
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
14601096PubMed ID
10.1002/cncr.11775DOI
Classification:
NotationType
Administration, OralMESH
AdultMESH
AgedMESH
Angiogenesis Inhibitors/pharmacologyMESH
Antineoplastic Combined Chemotherapy Protocols/therapeutic useMESH
Cyclophosphamide/analogs & derivativesMESH
Disease ProgressionMESH
Disease-Free SurvivalMESH
FemaleMESH
Hemangioendothelioma/pathologyMESH
Hemangiosarcoma/pathologyMESH
HumansMESH
Lactones/administration & dosageMESH
MaleMESH
Middle AgedMESH
SulfonesMESH
Thiazolidinediones/administration & dosageMESH
Treatment OutcomeMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 05:44
Last Modified:20 Apr 2010 05:44
Item ID:14424
Owner Only: item control page
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