Haenssle, Holger A. and Krause, Stefan W. and Emmert, Steffen and Zutt, Markus and Kretschmer, Lutz and Schmidberger, Heinz and Andreesen, Reinhard and Soruri, Afsaneh (2004) Hybrid cell vaccination in metastatic melanoma: clinical and immunologic results of a phase I/II study. Journal of immunotherapy (Hagerstown, Md. : 1997) 27 (2), pp. 147-55.
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Hybrid cell vaccination with cell fusion products (CFPs) of autologous tumor cells and mature allogenic MHC II bearing dendritic cells has been described to induce cytotoxic T lymphocyte (CTL)-mediated immune responses. The aim of this study was to assess safety, antitumor activity, and immune responses of a CFP-vaccine in patients with disseminated malignant melanoma. In a phase I/II study, we ...
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|Institutions:||Medicine > Abteilung für Hämatologie und Internistische Onkologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||20 Apr 2010 05:43|
|Last Modified:||20 Apr 2010 05:43|