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Expression and function of homing-essential molecules and enhanced in vivo homing ability of human peripheral blood-derived hematopoietic progenitor cells after stimulation with stem cell factor

Hart, Christina and Drewel, Diana and Mueller, Gunnar and Grassinger, Jochen and Zaiss, Matthias and Kunz-Schughart, Leoni A. and Andreesen, Reinhard and Reichle, Albrecht and Holler, Ernst and Hennemann, Burkhard (2004) Expression and function of homing-essential molecules and enhanced in vivo homing ability of human peripheral blood-derived hematopoietic progenitor cells after stimulation with stem cell factor. Stem cells (Dayton, Ohio) 22 (4), pp. 580-9.

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Abstract

Hematopoietic stem cell (HSC) homing from blood to bone marrow is a multistep process involving rolling, extravasation, migration, and finally adhesion in the correct microenvironment. With view to the hematopoietic recovery after clinical stem cell transplantation, we investigated the effect of stem cell factor (SCF) on the expression and the adhesive function of the alpha4beta1 and alpha5beta1 ...

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Item Type:Article
Date:2004
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
15277703PubMed ID
10.1634/stemcells.22-4-580DOI
Classification:
NotationType
Antigens, CD/bloodMESH
Antigens, CD34/bloodMESH
Base SequenceMESH
Biological Markers/bloodMESH
Cell AdhesionMESH
Cell Culture Techniques/methodsMESH
Colony-Forming Units AssayMESH
DNA PrimersMESH
Flow CytometryMESH
Granulocyte Colony-Stimulating Factor/therapeutic useMESH
Hematopoietic Stem Cell MobilizationMESH
HumansMESH
Integrin alpha4beta1/geneticsMESH
Integrin alpha5beta1/geneticsMESH
Polymerase Chain ReactionMESH
Stem Cell Transplantation/methodsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 05:44
Last Modified:20 Apr 2010 05:44
Item ID:14429
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