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Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells

Hoffmann, Petra and Eder, Ruediger and Kunz-Schughart, Leoni A and Andreesen, Reinhard and Edinger, Matthias (2004) Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells. Blood 104 (3), pp. 895-903.

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Abstract

CD4(+)CD25+ regulatory T (Treg) cells are pivotal for the maintenance of self-tolerance, and their adoptive transfer gives protection from autoimmune diseases and pathogenic alloresponses after solid organ or bone marrow transplantation in murine model systems. In vitro, human CD4(+)CD25+ Treg cells display phenotypic and functional characteristics similar to those of murine CD4(+)CD25+ Treg ...

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Item Type:Article
Date:2004
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
15090447PubMed ID
10.1182/blood-2004-01-0086DOI
Classification:
NotationType
AnimalsMESH
Antigens, CD/immunologyMESH
CD4-Positive T-Lymphocytes/immunologyMESH
Flow CytometryMESH
HumansMESH
L Cells (Cell Line)MESH
Lymphocyte Activation/immunologyMESH
Lymphocyte Culture Test, MixedMESH
MiceMESH
Receptors, IgG/immunologyMESH
Receptors, Interleukin-2/immunologyMESH
T-Lymphocytes/immunologyMESH
TransfectionMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 05:41
Last Modified:20 Apr 2010 05:41
Item ID:14431
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