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Impact of thrombophilic gene mutations and graft-versus-host disease on thromboembolic complications after allogeneic hematopoietic stem-cell transplantation

Pihusch, Markus and Lohse, Peter and Reitberger, Jill and Hiller, Erhard and Andreesen, Reinhard and Kolb, Hans-Jochem and Holler, Ernst and Pihusch, Rudolf (2004) Impact of thrombophilic gene mutations and graft-versus-host disease on thromboembolic complications after allogeneic hematopoietic stem-cell transplantation. Transplantation 78 (6), pp. 911-8.

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Abstract

BACKGROUND: Hemostatic events in patients undergoing allogeneic hematopoietic stem-cell transplantation (HSCT) increase the morbidity and mortality in this cohort. Little is known about the impact of graft-versus-host disease (GvHD) or of thrombophilic gene mutations/polymorphisms on these complications. STUDY DESIGN: Eighty-nine allogeneic stem-cell recipients and their donors were evaluated ...

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Item Type:Article
Date:2004
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
15385813PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
FemaleMESH
Graft vs Host Disease/geneticsMESH
HumansMESH
MaleMESH
Methylenetetrahydrofolate Reductase (NADPH2)/geneticsMESH
Middle AgedMESH
Mutation, Missense/geneticsMESH
Polymorphism, Single Nucleotide/geneticsMESH
Prothrombin/geneticsMESH
Stem Cell Transplantation/adverse effectsMESH
Thromboembolism/geneticsMESH
Transplantation, HomologousMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 05:25
Last Modified:20 Apr 2010 05:25
Item ID:14437
Owner Only: item control page
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