Hofstaedter, Ferdinand (1980) Frequency and morphology of malignant tumours of the thyroid before and after the introduction of iodine prophylaxis. Virchows Archiv A: Pathol. Anat. 385, pp. 263-270.
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Summary Reclassification of malignant goitres surgically removed between 1952–1975 reveals remarkable epidemiological alterations. There is a proportional decrease in undifferentiated carcinoma, which in males also represents an absolute decrease. The decrease is due to a change in maximum incidence from the 5th to the 7th decade. Differentiated carcinomas, especially the papillary tumours, increase. Comparison with findings in Switzerland shows many conformities. Iodine-prophylaxis apparently influences the morphology of thyroid carcinoma, as indicated by the time lag between the introduction of iodine-prophylaxis and the appearance of alterations in incidence. Iodine-prophylaxis, acting in this way, will improve survival rates in thyroid cancer.
|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||21 Apr 2010 10:53|
|Last Modified:||21 Apr 2010 10:53|
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