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Microsatellite instability: new aspects in the carcinogenesis of colorectal carcinoma

Rüschoff, J. and Bocker, T. and Schlegel, J. and Stumm, G. and Hofstaedter, Ferdinand (1995) Microsatellite instability: new aspects in the carcinogenesis of colorectal carcinoma. Virchows Archiv: an international journal of pathology 426 (3), pp. 215-222.

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Abstract

Very recently a new molecular mechanism in the tumorigenesis of colorectal carcinoma has been described which is closely linked to hereditary non-polyposis colonic cancer (HNPCC). Ubiquitous changes in the length of simple repetitive DNA sequences between constitutional and tumour DNA occur in about 90% of cases of HNPCC and in about 15% of cases of non-familial, sporadic colorectal carcinoma. ...

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Item Type:Article
Date:1995
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
7773499PubMed ID
Classification:
NotationType
Carcinogens/pharmacologyMESH
Carcinoma/geneticsMESH
Colorectal Neoplasms/geneticsMESH
DNA Repair/physiologyMESH
DNA, Satellite/geneticsMESH
FemaleMESH
HumansMESH
MaleMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:21 Apr 2010 08:42
Last Modified:21 Apr 2010 08:42
Item ID:14463
Owner Only: item control page
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