Startseite UB

Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion

Hoffmann, Petra and Eder, Ruediger and Boeld, Tina J and Doser, Kristina and Piseshka, Biserka and Andreesen, Reinhard and Edinger, Matthias (2006) Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion. Blood 108 (13), pp. 4260-7.

Full text not available from this repository.

at PubMed

at publisher (via DOI)


Abstract

Thymus-derived CD4+ CD25+ regulatory T cells suppress autoreactive CD4+ and CD8+ T cells and thereby protect from autoimmunity. In animal models, adoptive transfer of CD4+ CD25+ regulatory T cells has been shown to prevent and even cure autoimmune diseases as well as pathogenic alloresponses after solid organ and stem-cell transplantations. We recently described methods for the efficient in vitro ...

plus


Export bibliographical data

Item Type:Article
Date:2006
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
16917003PubMed ID
10.1182/blood-2006-06-027409DOI
Classification:
NotationType
Antigens, CD/immunologyMESH
Antigens, CD45/immunologyMESH
Antigens, Differentiation/immunologyMESH
Cell Differentiation/immunologyMESH
Cell ProliferationMESH
Cells, CulturedMESH
Cytokines/immunologyMESH
FemaleMESH
Forkhead Transcription Factors/immunologyMESH
Gene Expression Regulation/immunologyMESH
HumansMESH
Immunotherapy, AdoptiveMESH
L-Selectin/immunologyMESH
MaleMESH
Receptors, CCR7MESH
Receptors, Chemokine/immunologyMESH
T-Lymphocytes, Regulatory/metabolismMESH
Thymus Gland/metabolismMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 09:37
Last Modified:20 Apr 2010 09:37
Item ID:14488
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact