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Differentiation of human tumour-associated dendritic cells into endothelial-like cells: an alternative pathway of tumour angiogenesis

Gottfried, E. and Kreutz, M. and Haffner, S. and Holler, E. and Iacobelli, M. and Andreesen, Reinhard and Eissner, G. (2007) Differentiation of human tumour-associated dendritic cells into endothelial-like cells: an alternative pathway of tumour angiogenesis. Scandinavian journal of immunology 65 (4), pp. 329-35.

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Abstract

Until recently, the only accepted mechanism of tumour vascularization was the sprouting of endothelial cells (EC) from pre-existing vessels, while recent studies suggest the contribution of stem cell-derived endothelial progenitors as well as cells from the myeloid lineage. Here, we show a new way of endothelial differentiation that involves the specific modulation of monocytes by the tumour ...

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Item Type:Article
Date:2007
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
17386023PubMed ID
10.1111/j.1365-3083.2007.01903.xDOI
Classification:
NotationType
Cell Differentiation/immunologyMESH
Cell Lineage/immunologyMESH
Cells, CulturedMESH
Dendritic Cells/immunologyMESH
Endothelial Cells/immunologyMESH
Flow CytometryMESH
HumansMESH
ImmunohistochemistryMESH
Neoplasms/blood supplyMESH
Neovascularization, Pathologic/metabolismMESH
Oncostatin M/metabolismMESH
Vascular Endothelial Growth Factor A/metabolismMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2010 09:26
Last Modified:20 Apr 2010 09:26
Item ID:14500
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