Koehl, Gudrun E. and Geissler, Edward K. and Iacobelli, Massimo and Frei, Caroline and Burger, Verena and Haffner, Silvia and Holler, Ernst and Andreesen, Reinhard and Schlitt, Hans J. and Eissner, Günther (2007) Defibrotide: an endothelium protecting and stabilizing drug, has an anti-angiogenic potential in vitro and in vivo. Cancer biology & therapy 6 (5), pp. 686-90.
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Defibrotide (DF) is a polydisperse mixture of 90% single-stranded oligonucleotides with anti-thrombotic and anti-apoptotic functions. DF is used in the treatment of endothelial complications in the course of allogeneic stem cell transplantation. Recent preclinical evidence suggests that DF might also have anti-neoplastic properties. In the present study we hypothesized that DF might inhibit ...
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|Institutions:||Medicine > Abteilung für Hämatologie und Internistische Onkologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||20 Apr 2010 09:25|
|Last Modified:||20 Apr 2010 09:25|