Schlitt, Hans-Jürgen and Schwinzer, R. and Wonigeit, K. (1993) Responsiveness for mouse IgG2b antibodies to the human alpha/beta T-cell receptor/CD3 complex: evidence for genetic determination and low grade antibody cross-linking not mediated by known Fc gamma receptors. Scandinavian journal of immunology 37 (3), pp. 329-336.
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Mouse IgG2a and IgG3 antibodies directed to the human T-cell receptor/CD3 complex stimulate peripheral blood mononuclear cells in almost all individuals. By contrast, responder and non-responder individuals exist for the stimulatory effect of mouse IgG1 and IgG2b antibodies. Whereas responsiveness to IgG1 antibodies is rather frequent (60-70%) and is known to be determined by an Fc gamma RII ...
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|Institutions:||Medicine > Lehrstuhl für Chirurgie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||10 May 2010 12:12|
|Last Modified:||13 Mar 2014 13:23|