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Ciclosporin metabolite pattern in blood and urine of liver graft recipients. I. Association of ciclosporin metabolites with nephrotoxicity

Christians, U. and Kohlhaw, K. and Budniak, J. and Bleck, J. S. and Schottmann, R. and Schlitt, Hans-Jürgen and Almeida, V. M. and Deters, M. and Wonigeit, K. and Pichlmayr, R. (1991) Ciclosporin metabolite pattern in blood and urine of liver graft recipients. I. Association of ciclosporin metabolites with nephrotoxicity. European journal of clinical pharmacology 41 (4), pp. 285-290.

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Abstract

Blood ciclosporin (Cs) metabolite pattern in 58 liver grafted patients was routinely monitored by HPLC from the first Cs dose after transplantation until discharge from hospital. Eighteen patients with normal kidney function were allocated to Group I and 14 patients in Group II suffered Cs nephrotoxicity during their clinical course. There were no significant differences between both groups in ...

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Item Type:Article
Date:1991
Institutions:Medicine > Lehrstuhl für Chirurgie
Identification Number:
ValueType
1804640PubMed ID
10.1007/BF00314953DOI
Classification:
NotationType
AdultMESH
Chromatography, High Pressure LiquidMESH
Cyclosporine/urineMESH
HumansMESH
Kidney/physiologyMESH
Liver/physiologyMESH
Liver TransplantationMESH
Keywords:Ciclosporin liver transplantation; metabolites; nephrotoxicity
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Martin Kaiser
Deposited On:10 May 2010 12:18
Last Modified:13 Mar 2014 13:23
Item ID:14721
Owner Only: item control page

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