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Different activation states of human lymphocytes after antibody-mediated stimulation via CD3 and the alpha/beta T-cell receptor

Schlitt, Hans-Jürgen and Schwinzer, R. and Wonigeit, K. (1990) Different activation states of human lymphocytes after antibody-mediated stimulation via CD3 and the alpha/beta T-cell receptor. Scandinavian journal of immunology 32 (6), pp. 717-726.

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Abstract

BMA031 is an IgG2b antibody directed towards the human alpha/beta T-cell receptor that is able to induce proliferation of peripheral blood mononuclear cells independent of antibody crosslinking. The proliferative response to BMA031 during the first 3 days of culture is usually of similar magnitude to that induced by the IgG2a CD3 antibody OKT3 but decreases quickly afterwards. Stimulation by ...

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Item Type:Article
Date:December 1990
Institutions:Medicine > Lehrstuhl für Chirurgie
Identification Number:
ValueType
2148645PubMed ID
10.1111/j.1365-3083.1990.tb03215.xDOI
Classification:
NotationType
Antibodies, Monoclonal/diagnostic useMESH
Antigens, CD3MESH
Antigens, Differentiation/analysisMESH
Antigens, Differentiation, T-Lymphocyte/physiologyMESH
Cyclosporins/pharmacologyMESH
Cytotoxicity, ImmunologicMESH
HumansMESH
Interleukin-2/biosynthesisMESH
KineticsMESH
Lymphocyte Activation/immunologyMESH
Muromonab-CD3MESH
PhenotypeMESH
Receptors, Antigen, T-Cell/physiologyMESH
Receptors, Antigen, T-Cell, alpha-betaMESH
Receptors, Interleukin-2/physiologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Martin Kaiser
Deposited On:10 May 2010 12:26
Last Modified:13 Mar 2014 13:24
Item ID:14729
Owner Only: item control page

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