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Characterization of the new bladder cancer cell line HOK-1: expression of transitional, squamous and glandular differentiation patterns

Offner, F. A. and Ott, G. and Povey, S. and Knuechel, R. and Preisler, V. and Fuezesi, L. and Klosterhalfen, B. and Ruebben, H. and Hofstaedter, Ferdinand and Kirkpatrick, C. J. (1991) Characterization of the new bladder cancer cell line HOK-1: expression of transitional, squamous and glandular differentiation patterns. International journal of cancer 49 (1), pp. 122-128.

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Abstract

The new continuous cell line HOK-1 derived from a grade-III transitional-cell bladder carcinoma with foci of squamous and glandular differentiation was shown to retain this phenotypical heterogeneity for more than 45 passages in vitro. Electron microscopy revealed transitional as well as a considerable proportion of squamous carcinoma and adenocarcinoma cells. PAS-positive mucus was detected in ...

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Item Type:Article
Date:1991
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
1714884PubMed ID
Classification:
NotationType
AgedMESH
Blood Group AntigensMESH
Carcinoma, Squamous Cell/pathologyMESH
Carcinoma, Transitional Cell/pathologyMESH
Cell DifferentiationMESH
DNA, Neoplasm/analysisMESH
FemaleMESH
HLA Antigens/analysisMESH
HumansMESH
Isoenzymes/analysisMESH
KaryotypingMESH
Keratins/metabolismMESH
Microscopy, ElectronMESH
Tumor Cells, Cultured/cytologyMESH
Tumor Markers, Biological/analysisMESH
Urinary Bladder Neoplasms/pathologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:09 Jun 2010 14:54
Last Modified:09 Jun 2010 14:54
Item ID:15253
Owner Only: item control page
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