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Induction of intestinal mucosal atrophy by difluoromethylornithine: a nonuremic model of enhanced aluminum absorption

Ittel, T. H. and Paulus, C. P. and Handt, S. and Hofstädter, Ferdinand and Sieberth, H. G. (1992) Induction of intestinal mucosal atrophy by difluoromethylornithine: a nonuremic model of enhanced aluminum absorption. Mineral and electrolyte metabolism 18 (1), pp. 15-23.

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Abstract

The intestinal absorption of aluminum (Al) appears to be enhanced in the uremic rat. Since atrophic changes of the intestinal mucosa have been observed in uremia the present study investigated whether intestinal atrophy induced by difluoromethylornithine (DFMO), a specific inhibitor of ornithine decarboxylase, could affect the absorption of Al. DFMO supplied with the drinking water (5%) to rats ...

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Item Type:Article
Date:1992
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
1406501PubMed ID
Classification:
NotationType
Aluminum/urineMESH
AnimalsMESH
Atrophy/chemically inducedMESH
Eflornithine/pharmacologyMESH
Intestinal AbsorptionMESH
Intestinal Mucosa/pathologyMESH
KineticsMESH
MaleMESH
Microscopy, ElectronMESH
Microvilli/pathologyMESH
Ornithine Decarboxylase/metabolismMESH
RatsMESH
Rats, Sprague-DawleyMESH
Uremia/pathologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:09 Jun 2010 14:48
Last Modified:09 Jun 2010 14:48
Item ID:15258
Owner Only: item control page
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