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Comparative genomic in situ hybridization of colon carcinomas with replication error

Schlegel, J. and Stumm, G and Scherthan, H. and Bocker, T. and Zirngibl, H. and Rüschoff, J. and Hofstädter, Ferdinand (1995) Comparative genomic in situ hybridization of colon carcinomas with replication error. Cancer research 55 (24), pp. 6002-6005.

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Abstract

The aim of the present study was to detect complex genetic alterations in colorectal carcinomas with and without microsatellite instability (MIN) by comparative genomic in situ hybridization. MIN due to replication errors is the hallmark of hereditary nonpolyposis colon cancer. None of 6 MIN-positive tumors showed amplifications, and only 2 tumors displayed deletions of one chromosomal segment ...

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Item Type:Article
Date:1995
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
8521381PubMed ID
Classification:
NotationType
AdultMESH
AgedMESH
Chromosome Aberrations/geneticsMESH
Chromosome DisordersMESH
Colorectal Neoplasms/geneticsMESH
DNA ReplicationMESH
DNA, Neoplasm/geneticsMESH
Gene AmplificationMESH
HumansMESH
In Situ HybridizationMESH
Microsatellite RepeatsMESH
Middle AgedMESH
Polymerase Chain ReactionMESH
Sequence DeletionMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:14 Jun 2010 06:15
Last Modified:14 Jun 2010 06:15
Item ID:15307
Owner Only: item control page
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