Fickweiler, S. and Steinbach, P. and Wörle, K. and Hofstädter, Ferdinand (1996) The combined effects of high-energy shock waves and ionising radiation on a human bladder cancer cell line. Ultrasound in medicine & biology 22 (8), pp. 1097-1102.
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The effects of high-energy shock waves (HESW) generated by an experimental Siemens lithotripter in combination with 137Cs gamma-rays were examined in vitro. Proliferation after treatment of immobilised pellets of either single cells or multicellular spheroids of the bladder cancer cell line RT4 was determined using colony-forming assays and cell cycle analysis. Surviving and cell cycle fractions were calculated for each shock wave and radiation application mode separately, and for sequential combination in different successions for the purpose of characterizing the interaction of both treatment modalities. Combination of HESW and ionising radiation turned out to act additively or slightly supra-additively on both biologic models.
|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||17 Jun 2010 08:34|
|Last Modified:||17 Jun 2010 08:34|