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Photosensitization of skin-derived cell lines by Dimegin [2,4-di-(alpha-methoxyethyl)-deuteroporphyrin IX] in vitro

Fickweiler, S. and Szeimies, R. M. and Abels, C. and Ponomarev, G. V. and Hofstädter, Ferdinand and Wolfbeis, O. S. and Landthaler, M. (1998) Photosensitization of skin-derived cell lines by Dimegin [2,4-di-(alpha-methoxyethyl)-deuteroporphyrin IX] in vitro. Photodermatology, photoimmunology & photomedicine 14 (3-4), pp. 125-131.

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Abstract

The deuteroporphyrin-IX derivative Dimegin [2,4-di-(alpha-methoxyethyl)-deuteroporphyrin IX] was investigated with respect to cellular uptake, intracellular localization and cell survival following photodynamic treatment in human cell lines derived from the skin (SCL1 and SCL2, squamous cell carcinoma; HaCaT keratinocytes; N1 fibroblasts). Using flow cytometry, we determined the cellular ...

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Item Type:Article
Date:1998
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
9779501PubMed ID
Classification:
NotationType
Carcinoma, Squamous Cell/pathologyMESH
Cell LineMESH
Cell SurvivalMESH
Deuteroporphyrins/pharmacologyMESH
Flow CytometryMESH
HumansMESH
Microscopy, FluorescenceMESH
Photosensitizing Agents/toxicityMESH
Skin/pathologyMESH
Spectrometry, FluorescenceMESH
Tumor Cells, Cultured/pathologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:17 Jun 2010 08:57
Last Modified:17 Jun 2010 08:57
Item ID:15348
Owner Only: item control page
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