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Multiple mutation analyses in single tumor cells with improved whole genome amplification

Dietmaier, W. and Hartmann, A. and Wallinger, S. and Heinmöller, E. and Kerner, T. and Endl, E. and Jauch, K. W. and Hofstädter, Ferdinand and Rüschoff, J. (1999) Multiple mutation analyses in single tumor cells with improved whole genome amplification. The American journal of pathology 154 (1), pp. 83-95.

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Abstract

Combining whole genome amplification (WGA) methods with novel laser-based microdissection techniques has made it possible to exploit recent progress in molecular knowledge of cancer development and progression. However, WGA of one or a few cells has not yet been optimized and systematically evaluated for samples routinely processed in tumor pathology. We therefore studied the value of established ...

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Item Type:Article
Date:1999
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
1382568PubMed ID
Classification:
NotationType
Bone Marrow Neoplasms/pathologyMESH
Breast Neoplasms/pathologyMESH
Cell SeparationMESH
DNA Mutational AnalysisMESH
DNA PrimersMESH
DNA, Neoplasm/geneticsMESH
Feasibility StudiesMESH
FemaleMESH
Genes, ras/geneticsMESH
GenomeMESH
HumansMESH
Loss of HeterozygosityMESH
Microsatellite RepeatsMESH
Neoplasms/pathologyMESH
Paraffin EmbeddingMESH
Polymerase Chain Reaction/methodsMESH
Tumor Cells, CulturedMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:17 Jun 2010 08:18
Last Modified:17 Jun 2010 08:18
Item ID:15353
Owner Only: item control page
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