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Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells

Brockhoff, G. and Heiss, P. and Schlegel, J. and Hofstaedter, Ferdinand and Knuechel, R. (2001) Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells. Cytometry 44 (4), pp. 338-348.

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Abstract

BACKGROUND: Receptors belonging to the epidermal growth factor receptor (EGFR) family transfer extracellular signals by homotypic and heterotypic receptor interaction and cross-activation. Cell differentiation, death, and proliferation are regulated via these receptor-tyrosine-kinases. However, the initial mechanisms that lead to signal specificity and diversity, which cause a defined cellular ...

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Item Type:Article
Date:2001
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
11500850PubMed ID
Classification:
NotationType
Breast Neoplasms/pathologyMESH
Cell Cycle/physiologyMESH
Cell Division/physiologyMESH
Epidermal Growth Factor/pharmacologyMESH
FemaleMESH
G1 Phase/physiologyMESH
HumansMESH
Macromolecular SubstancesMESH
Mitogen-Activated Protein Kinase Kinases/metabolismMESH
Neuregulin-1/pharmacologyMESH
Protein Binding/physiologyMESH
Protein-Serine-Threonine KinasesMESH
Proto-Oncogene Proteins/metabolismMESH
Proto-Oncogene Proteins c-aktMESH
Receptor, Epidermal Growth Factor/metabolismMESH
Receptor, erbB-2/metabolismMESH
Receptor, erbB-3/metabolismMESH
Signal TransductionMESH
Tumor Cells, CulturedMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:18 Jun 2010 08:57
Last Modified:18 Jun 2010 08:57
Item ID:15396
Owner Only: item control page
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