Jeschke, M. G. and Richter, G. and Hofstädter, Ferdinand and Herndon, D. N. and Perez-Polo, J.-R. and Jauch, K.-W. (2002) Non-viral liposomal keratinocyte growth factor (KGF) cDNA gene transfer improves dermal and epidermal regeneration through stimulation of epithelial and mesenchymal factors. Gene therapy 9 (16), pp. 1065-1074.
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Keratinocyte growth factor (KGF) stimulates epithelial cell differentiation and proliferation, which are of major importance for wound healing. Local protein administration, however, has been shown to be ineffective due to enzymes and proteases in the wound fluid. We hypothesized that delivering KGF as a non-viral liposomal cDNA gene complex is a new approach that would effectively enhance dermal ...
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|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Yes|
|Deposited On:||18 Jun 2010 08:53|
|Last Modified:||18 Jun 2010 08:53|