Stoehr, Robert and Knuechel, Ruth and Boecker, Joerg and Blaszyk, Hagen and Schmitt, Ruediger and Filbeck, Thomas and Hofstaedter, Ferdinand and Hartmann, Arndt (2002) Histologic-genetic mapping by allele-specific PCR reveals intraurothelial spread of p53 mutant tumor clones. Laboratory investigation 82 (11), pp. 1553-1561.
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Common and clinically important features of urothelial carcinomas are multifocality and a high rate of recurrence. Molecular studies demonstrated that multifocal tumors are frequently composed of one tumor clone spreading throughout the urothelial tract. A combination of histologic and genetic mapping of cystectomy specimens from bladder cancer patients is a valuable tool to study bladder ...
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|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Dewey Decimal Classification:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited on:||18 Jun 2010 08:34|
|Last modified:||18 Jun 2010 08:34|