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Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer

Stoehr, Robert and Wissmann, Christoph and Suzuki, Hiromu and Knuechel, Ruth and Krieg, Rene C. and Klopocki, Eva and Dahl, Edgar and Wild, Peter and Blaszyk, Hagen and Sauter, Guido and Simon, Ronald and Schmitt, Ruediger and Zaak, Dirk and Hofstaedter, Ferdinand and Rosenthal, Andre and Baylin, Stephen B. and Pilarsky, Christian and Hartmann, Arndt (2004) Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer. Laboratory investigation 84 (4), pp. 465-478.

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Abstract

Many molecular alterations are known to occur in urothelial carcinoma of the bladder, but their significance for tumor progression is poorly understood. Deletions of chromosome 8p are frequently found in several tumor types and are often associated with progressive disease. In all, 99 bladder tumors were screened for deletions at 8p using loss of heterozygosity (LOH) and multicolor fluorescence ...

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Item Type:Article
Date:2004
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
14968126PubMed ID
10.1038/labinvest.3700068DOI
Classification:
NotationType
Blotting, NorthernMESH
Cell Line, TumorMESH
Chromosome DeletionMESH
Chromosomes, Human, Pair 8MESH
DNA MethylationMESH
Disease ProgressionMESH
HumansMESH
ImmunohistochemistryMESH
In Situ Hybridization, FluorescenceMESH
Intercellular Signaling Peptides and Proteins/geneticsMESH
Loss of HeterozygosityMESH
Membrane Proteins/geneticsMESH
Promoter Regions, GeneticMESH
Reverse Transcriptase Polymerase Chain ReactionMESH
Tumor Markers, BiologicalMESH
Urinary Bladder Neoplasms/geneticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:18 Jun 2010 08:32
Last Modified:18 Jun 2010 08:32
Item ID:15418
Owner Only: item control page
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