Bettstetter, Marcus and Dechant, Stefan and Ruemmele, Petra and Vogel, Corinna and Kurz, Katrin and Morak, Monika and Keller, Gisela and Holinski-Feder, Elke and Hofstaedter, Ferdinand and Dietmaier, Wolfgang (2008) MethyQESD, a robust and fast method for quantitative methylation analyses in HNPCC diagnostics using formalin-fixed and paraffin-embedded tissue samples. Laboratory investigation 88 (12), pp. 1367-1375.
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Promoter hypermethylation occurs in various tumors and leads to silencing of tumor-relevant genes. Thus, promoter methylation analysis (MA) has been established as an important tool in cancer research and diagnostics. Here we present MethyQESD (methylation-quantification of endonuclease-resistant DNA) as a fast, easy, precise and reliable method for quantitative MA without the need of ...
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|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||18 Jun 2010 08:31|
|Last Modified:||18 Jun 2010 08:31|