Stoehr, Robert and Brinkmann, Anke and Filbeck, Thomas and Gamper, Christoph and Wild, Peter and Blaszyk, Hagen and Hofstaedter, Ferdinand and Knuechel, Ruth and Hartmann, Arndt (2004) No evidence for mutation of B-RAF in urothelial carcinomas of the bladder and upper urinary tract. Oncology reports 11 (1), pp. 137-141.
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Mutational activation of the MAP kinase pathway is frequently found in various cancers. Recently, activating mutations in the B-RAF gene, an important activator of this pathway, have been described in several tumor types including melanoma, colorectal and papillary thyroid cancer. The most frequent mutation in exon 15 (V599E), as well as several other mutations within exons 11 and 15 result in ...
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|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||22 Jun 2010 09:54|
|Last Modified:||22 Jun 2010 09:54|