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Microsatellite instability predicts poor short-term survival in patients with advanced breast cancer after high-dose chemotherapy and autologous stem-cell transplantation

Wild, Peter J. and Reichle, Albrecht and Andreesen, Reinhard and Röckelein, Georg and Dietmaier, Wolfgang and Rüschoff, Josef and Blaszyk, Hagen and Hofstädter, Ferdinand and Hartmann, Arndt (2004) Microsatellite instability predicts poor short-term survival in patients with advanced breast cancer after high-dose chemotherapy and autologous stem-cell transplantation. Clinical cancer research 10 (2), pp. 556-564.

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Abstract

PURPOSE: The purpose is to define molecular prognostic factors in patients with advanced breast cancer treated with high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT). EXPERIMENTAL DESIGN: Thirty-nine patients with breast cancer and extensive lymph node (level III) and/or systemic metastases from a prospective single-center study of sequential HDCT/ASCT were studied. ...

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Item Type:Article
Date:2004
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
14760077PubMed ID
Classification:
NotationType
AdultMESH
Breast Neoplasms/mortalityMESH
ExonsMESH
FemaleMESH
Genes, p53MESH
HumansMESH
ImmunohistochemistryMESH
Lymphatic MetastasisMESH
MenopauseMESH
Microsatellite RepeatsMESH
Middle AgedMESH
PrognosisMESH
Proportional Hazards ModelsMESH
Receptor, erbB-2/metabolismMESH
Stem Cell TransplantationMESH
Time FactorsMESH
Treatment OutcomeMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:22 Jun 2010 09:46
Last Modified:22 Jun 2010 09:46
Item ID:15435
Owner Only: item control page
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