Hafner, Christian and Hartmann, Arndt and van Oers, Johanna M. M. and Stoehr, Robert and Zwarthoff, Ellen C. and Hofstaedter, Ferdinand and Landthaler, Michael and Vogt, Thomas (2007) FGFR3 mutations in seborrheic keratoses are already present in flat lesions and associated with age and localization. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20 (8), pp. 895-903.
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Somatic activating fibroblast growth factor 3 (FGFR3) mutations in human skin can cause seborrheic keratoses, one of the most frequent skin tumors in man. However, details of the involved mechanisms remain elusive. We analyzed 65 acanthotic seborrheic keratoses with varying vertical diameters for FGFR3 mutations using a SNaPshot multiplex assay. Immunohistochemistry was performed for Ki-67, bcl-2 ...
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|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||22 Jun 2010 14:05|
|Last Modified:||22 Jun 2010 14:05|