Hoenicka, Markus and Schmid, Christof (2008) Cardiovascular effects of modulators of soluble guanylyl cyclase activity. Cardiovascular & hematological agents in medicinal chemistry 6 (4), pp. 287-301.
Soluble guanylyl cyclase (sGC) is one of the key enzymes of the nitric-oxide (NO)/cyclic 3',5'-guanosine monophosphate (cGMP) pathway. Located in virtually all mammalian cells, it controls the vessel tone, smooth muscle cell growth, platelet aggregation, and leukocyte adhesion. In vivo sGC activity is mainly regulated by NO which in turn is released from L-arginine by nitric oxide synthases. One ...
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|Institutions:||Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||05 Jul 2010 15:31|
|Last Modified:||13 Mar 2014 13:45|