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Ditopic crown ether – guanidinium ion receptors for the molecular recognition of amino acids and small peptides

Späth, A. and König, Burkhard (2010) Ditopic crown ether – guanidinium ion receptors for the molecular recognition of amino acids and small peptides. Tetrahedron (66), pp. 1859-1873.

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Abstract

A series of ditopic synthetic receptors based on a crown ether–guanidinium ion recognition motif is reported. The compounds show binding affinity to selected amino acids, including important neurotransmitters. The effect of the distance of the ammonium and the carboxylate ion, the rigidity of the spacer, and the use of pre-organized pyrrole– and pyrene–guanidinium groups on binding affinity ...

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Item Type:Article
Date:2010
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1016/j.tet.2010.01.028DOI
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:05 Jul 2010 15:27
Last Modified:26 Oct 2010 12:06
Item ID:15667
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