Formation of 1H-Aziridines from Chalcones and Hydroxylamine

Kammermeier, T. and Kaiser, A. and Lee, G.S. and Burgemeister, Thomas and Wiegrebe, Wolfgang (1994) Formation of 1H-Aziridines from Chalcones and Hydroxylamine. Archiv der Pharmazie 327, pp. 207-210.

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Abstract

Highly substituted chalcones 1 do not react with two molecules of hydroxylamine
affording dioximes 2 or hydroxyamino-oximes 3 as expected
according to von Auwers' procedure1): only one molecule of hydroxylamine
is consumed leading to trans-configurated 2-benzoyl-3-phenyl-1H-aziridines 4.

Aus den hochsubstituierten Chalkonen 1 entstehen nicht die nach von
Auwers1) zu erwartenden Dioxime 2 oder Hydroxyamino-oxime 3 unter
Verbrauch von zwei Mol Hydroxylamin. Stattdessen wird nur ein Mol
Hydroxylamin verbraucht, und es entstehen trans-konfigurierte 2-Benzoyl-
3-phenyl-1H-aziridine 4.

Item Type:Article
Institutions: Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Wiegrebe
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner:Universitätsbibliothek Regensburg
Deposited On:12 Jul 2010 11:40
Last Modified:21 Jul 2011 00:32
Item ID:15793
Owner Only: item control page