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Effects of Shear Forces and Pressure on Blood Vessel Function and Metabolism in a Perfusion Bioreactor.

Hoenicka, Markus and Wiedemann, Ludwig and Puehler, Thomas and Hirt, Stephan and Birnbaum, Dietrich E and Schmid, Christof (2010) Effects of Shear Forces and Pressure on Blood Vessel Function and Metabolism in a Perfusion Bioreactor. Annals of biomedical engineering 38 (12), pp. 3706-3723.

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Abstract

Bovine saphenous veins (BSV) were incubated in a perfusion bioreactor to study vessel wall metabolism and wall structure under tissue engineering conditions. Group 1 vessels were perfused for 4 or 8 days. The viscosity of the medium was increased to that of blood in group 2. Group 3 vessels were additionally strained with luminal pressure. Groups 1-d through 3-d were similar except that BSV were ...

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Item Type:Article
Date:2010
Institutions:Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Identification Number:
ValueType
20614243PubMed ID
10.1007/s10439-010-0116-1DOI
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Markus Hoenicka
Deposited On:15 Jul 2010 09:33
Last Modified:13 Mar 2014 13:52
Item ID:15884
Owner Only: item control page
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