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Specificity and reversibility of chemotactic deactivation of human monocytes

Falk, Werner and Leonard, E.J. (1981) Specificity and reversibility of chemotactic deactivation of human monocytes. Infection and immunity 32 (2), pp. 464-468.

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Abstract

The chemotactic deactivation of human monocytes was studied to provide insight into the mechanism of chemotaxis. Deactivation was dependent on the dose of chemoattractant and time of incubation. A concentration in the cell suspension of 10(-8) M N-formylmethionylleucyl phenylalanine (FMLP) for 45 min at 37 degrees C led to 60% suppression of the subsequent specific chemotactic response. Higher ...

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Item Type:Article
Date:1981
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
5642465PubMed ID
Classification:
NotationType
Anaphylatoxins/pharmacologyMESH
Chemotactic Factors/pharmacologyMESH
Chemotaxis, Leukocyte/drug effectsMESH
Complement C5/pharmacologyMESH
Complement C5aMESH
Dose-Response Relationship, DrugMESH
Energy MetabolismMESH
HumansMESH
KineticsMESH
Methionine/analogs & derivativesMESH
Monocytes/physiologyMESH
N-Formylmethionine/pharmacologyMESH
N-Formylmethionine Leucyl-PhenylalanineMESH
Oligopeptides/pharmacologyMESH
Receptors, Cell Surface/metabolismMESH
Receptors, Formyl PeptideMESH
TemperatureMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Jul 2010 06:14
Last Modified:13 Mar 2014 13:53
Item ID:15958
Owner Only: item control page

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