Aksamit, R.R. and Falk, Werner and Cantoni, G.L. (1982) Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. The Journal of biological chemistry 257 (2), pp. 621-625.
Chemotaxis by a macrophage cell line, RAW264, is specifically inhibited by the intracellular accumulation of 3-deazaadenosylhomocysteine (3-deaza-AdoHcy). Intracellular accumulation of 3-deaza-AdoHcy is the result of incubation of the cells with 3-deazaadenosine, a compound that can function both as a substrate and as an inhibitor of adenosylhomocysteine (AdoHcy) hydrolase. Accumulation of AdoHcy ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin I|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||20 Jul 2010 09:15|
|Last Modified:||13 Mar 2014 13:53|