Startseite UB

Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line

Aksamit, R.R. and Falk, Werner and Cantoni, G.L. (1982) Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. The Journal of biological chemistry 257 (2), pp. 621-625.

[img]
Preview
PDF
Download (641kB)

at PubMed


Abstract

Chemotaxis by a macrophage cell line, RAW264, is specifically inhibited by the intracellular accumulation of 3-deazaadenosylhomocysteine (3-deaza-AdoHcy). Intracellular accumulation of 3-deaza-AdoHcy is the result of incubation of the cells with 3-deazaadenosine, a compound that can function both as a substrate and as an inhibitor of adenosylhomocysteine (AdoHcy) hydrolase. Accumulation of AdoHcy ...

plus


Export bibliographical data

Item Type:Article
Date:1982
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
7054170PubMed ID
Classification:
NotationType
AnimalsMESH
Cell LineMESH
Chemotaxis/drug effectsMESH
Homocysteine/analogs & derivativesMESH
IsomerismMESH
KineticsMESH
Macrophages/physiologyMESH
MiceMESH
S-Adenosylhomocysteine/pharmacologyMESH
Structure-Activity RelationshipMESH
Tubercidin/pharmacologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Jul 2010 09:15
Last Modified:13 Mar 2014 13:53
Item ID:15962
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact