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Only the chemotactic subpopulation of human blood monocytes expresses receptors for the chemotactic peptide N-formylmethionyl-leucyl-phenylalanine

Falk, Werner and Harvath, L. and Leonard, E.J. (1982) Only the chemotactic subpopulation of human blood monocytes expresses receptors for the chemotactic peptide N-formylmethionyl-leucyl-phenylalanine. Infection and immunity 36 (2), pp. 450-454.

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Abstract

Human peripheral blood monocytes comprise a subpopulation of 20 to 40% that is capable of responding to chemoattractants and a remaining subpopulation that cannot respond. We were able to obtain 99%-pure attractant-responsive monocytes by using a newly constructed separation chamber. The binding of the radioactive chemotactic peptide N-formylmethionyl-leucyl-[3H]phenylalanine to migrating and ...

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Item type:Article
Date:1982
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
836328PubMed ID
Classification:
NotationType
Azides/pharmacologyMESH
Binding SitesMESH
Cell SeparationMESH
Chemotaxis, LeukocyteMESH
HumansMESH
KineticsMESH
Methionine/analogs & derivativesMESH
Monocytes/physiologyMESH
N-Formylmethionine/metabolismMESH
N-Formylmethionine Leucyl-PhenylalanineMESH
Oligopeptides/metabolismMESH
Receptors, Cell Surface/metabolismMESH
Receptors, Formyl PeptideMESH
Sodium AzideMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Deposited on:20 Jul 2010 09:13
Last modified:13 Mar 2014 13:54
Item ID:15965
Owner only: item control page

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