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Interferon-gamma is required in activation of macrophages for tumor cytotoxicity

Männel, Daniela N. and Falk, Werner (1983) Interferon-gamma is required in activation of macrophages for tumor cytotoxicity. Cellular immunology 79 (2), pp. 396-402.

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Abstract

The participation of interferon-gamma in activation of murine macrophages for tumor cell lysis was investigated. Biochemically macrophage activation factor and interferon-gamma have not been separated. Antiviral titers correlated closely with macrophage activation in antigen- or mitogen-induced spleen cell supernatants. A monoclonal rat antibody that neutralized virus-induced interferon was also ...

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Item Type:Article
Date:1983
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
6307534PubMed ID
Classification:
NotationType
AnimalsMESH
Antibodies, Monoclonal/physiologyMESH
Cytotoxicity, ImmunologicMESH
FemaleMESH
Fibrosarcoma/immunologyMESH
Immunosorbent TechniquesMESH
Interferon-gamma/physiologyMESH
Interleukin-2/analysisMESH
Lymphokines/physiologyMESH
Macrophage ActivationMESH
Macrophage-Activating FactorsMESH
MaleMESH
MiceMESH
Mice, Inbred C3HMESH
Neutralization TestsMESH
RatsMESH
Rats, Inbred StrainsMESH
Vesicular stomatitis Indiana virus/growth & developmentMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:21 Jul 2010 05:06
Last Modified:13 Mar 2014 13:54
Item ID:15972
Owner Only: item control page

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