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Suppression of cytotoxic T lymphocyte activation by L-ornithine

Dröge, W. and Männel, D.N. and Falk, Werner and Lehmann, V. and Schmidt, H. and Nick, S. and Häcker-Shahin, B. and Jänicke, R. (1985) Suppression of cytotoxic T lymphocyte activation by L-ornithine. Journal of immunology (Baltimore, Md. : 1950) 134 (5), pp. 3379-3383.

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Abstract

The effect of L-ornithine on several types of immune reactions was analyzed. L-ornithine was found to suppress the activation of cytotoxic T lymphocytes (CTL) in vivo and in vitro. This suppressive effect was not observed with the structural analogues D-ornithine, L-lysine, or putrescine or with the amino acids L-histidine or L-alanine. The concentration of 9 X 10(-3) M L-ornithine was found to ...

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Item Type:Article
Date:1985
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
3920317PubMed ID
Classification:
NotationType
AnimalsMESH
Cytotoxicity, Immunologic/drug effectsMESH
DNA/biosynthesisMESH
Immunosuppressive Agents/pharmacologyMESH
Interferon-gamma/biosynthesisMESH
Interleukin-2/biosynthesisMESH
Lymphocyte Activation/drug effectsMESH
MiceMESH
Mice, Inbred C3HMESH
Mice, Inbred C57BLMESH
Ornithine/pharmacologyMESH
T-Lymphocytes, Cytotoxic/metabolismMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:21 Jul 2010 05:10
Last Modified:13 Mar 2014 13:54
Item ID:15975
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