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A combination of soluble helper factors bypasses the requirement for stimulator cells and induces nonspecific cytotoxic T cell responses

Männel, D.N. and Dröge, W. and Falk, Werner (1985) A combination of soluble helper factors bypasses the requirement for stimulator cells and induces nonspecific cytotoxic T cell responses. Immunobiology 170 (3), pp. 146-157.

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Abstract

The specificity of cytotoxic T lymphocyte (CTL) responses generated in the presence of lymphokines was studied. Thymic responder cells were activated in the presence of stimulator cells that differed in their metabolic activity. After 5 days of culture, the cytotoxic response was estimated in a 4-h 51Cr-release test. Coculture of thymic responders with irradiated splenic stimulator cells in the ...

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Item Type:Article
Date:1985
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
2414210PubMed ID
Classification:
NotationType
AnimalsMESH
Antigen-Presenting Cells/immunologyMESH
EpitopesMESH
Interleukin-2/immunologyMESH
Isoantigens/immunologyMESH
MiceMESH
Mice, Inbred StrainsMESH
T-Lymphocytes, Cytotoxic/immunologyMESH
T-Lymphocytes, Helper-Inducer/immunologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:21 Jul 2010 09:25
Last Modified:13 Mar 2014 14:04
Item ID:15980
Owner Only: item control page
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