Männel, D.N. and Mizel, S.B. and Diamantstein, T. and Falk, Werner
Induction of interleukin 2 responsiveness in thymocytes by synergistic action of interleukin 1 and interleukin 2.
Journal of immunology (Baltimore, Md. : 1950) 134 (5), pp. 3108-3110.
Thymocyte cultures from C3H/HeJ mice were stimulated for proliferative responses with purified preparations of interleukin 1 (IL 1) and interleukin 2 (IL 2). Synergistic responses were obtained in the absence of mitogen. In the presence of excess IL 2, the thymocyte proliferation response was strictly dependent on the amount of IL 1 in the cultures. Antibodies to IL 1 inhibited the response in a ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin I|
|Mice, Inbred C3H||MESH|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||21 Jul 2010 09:23|
|Last Modified:||13 Mar 2014 13:54|