Wolf, M. and Falk, Werner and Männel, D.N. and Dröge, W.
Inhibition of interleukin 2 production by prostaglandin E2 is not absolute but depends on the strength of the stimulating signal.
Cellular immunology 90 (1), pp. 190-195.
In view of the eminently important role of interleukin-2 (IL-2) in T-cell responses, and in view of reports about immune stimulatory effects of PGE2, we reinvestigated the question whether PGE2 inhibits IL-2 production. It was found that PGE2 does not inhibit IL-2 production in murine spleen cell cultures after optimal stimulation (5 micrograms/ml concanavalin A) but does inhibit at suboptimal ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin I|
|Dose-Response Relationship, Drug||MESH|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||21 Jul 2010 09:23|
|Last Modified:||13 Mar 2014 13:54|