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Nuclear architecture and structural dynamics - molecular basis of chromatin remodeling induced by human ISWI machines -

URN to cite this document: urn:nbn:de:bvb:355-epub-159929

Exler, Josef H. (2011) Nuclear architecture and structural dynamics - molecular basis of chromatin remodeling induced by human ISWI machines -. PhD, Universität Regensburg

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Abstract (English)

One striking observation made when revealing the genetic code of humans was the relative small number of protein encoding genes that were found. The increased complexity of this biological system was not reflected by an increased number of genes. Nevertheless for higher vertebrates an expansion in genome sizes was observed [Yoo and Crabtree, 2009]. Only a small fraction of the genetic code is ...

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Translation of the abstract (German)

Eine überraschende Beobachtung, die nach Sequenzierung des genetischen Codes des Menschen gemacht wurde, war die relativ kleine Anzahl von Protein-codierenden Genen, die gefunden wurde. Die erhöhte Komplexität dieses biologischen Systems spiegelte sich nicht in einer Erhöhung der Anzahl der Gene wider. Nichtsdestotrotz wurde eine Expansion der Genomgröße für höhere Wirbeltiere beobachtet [Yoo ...

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Item Type:Thesis of the University of Regensburg (PhD)
Date:10 August 2011
Referee:Prof. Dr. Gernot Längst and Prof. Dr. Reinhard Sterner and Prof. Dr. Ralf Wagner
Date of exam:15 July 2010
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III
Research groups and research centres:Not selected
Keywords:Chromatin Remodeling, SNF2H, SNF2L, kooperative Bindung, MNase, Zellkernarchitektur, aktive Chromatindomänen, ENCODE
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:10 Aug 2011 07:26
Last Modified:13 Mar 2014 17:48
Item ID:15992
Owner Only: item control page

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