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Monoclonal antibody-mediated tumor regression by induction of apoptosis

Trauth, B.C. and Klas, C. and Peters, A.M. and Matzku, S. and Möller, P. and Falk, Werner and Debatin, K.M. and Krammer, P.H. (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science (New York, N.Y.) 245 (4915), pp. 301-305.

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Abstract

To characterize cell surface molecules involved in control of growth of malignant lymphocytes, monoclonal antibodies were raised against the human B lymphoblast cell line SKW6.4. One monoclonal antibody, anti-APO-1, reacted with a 52-kilodalton antigen (APO-1) on a set of activated human lymphocytes, on malignant human lymphocyte lines, and on some patient-derived leukemic cells. Nanogram ...

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Item Type:Article
Date:1989
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
2787530PubMed ID
Classification:
NotationType
AnimalsMESH
Antibodies, Monoclonal/therapeutic useMESH
Antigens, Neoplasm/immunologyMESH
AutoradiographyMESH
B-Lymphocytes/immunologyMESH
Burkitt Lymphoma/therapyMESH
Cell SurvivalMESH
Cells, CulturedMESH
Electrophoresis, Polyacrylamide GelMESH
HumansMESH
Leukemia, B-Cell/therapyMESH
MiceMESH
Mice, NudeMESH
Precipitin TestsMESH
Remission InductionMESH
T-Lymphocytes/immunologyMESH
Tumor Cells, CulturedMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:08 Sep 2010 05:25
Last Modified:13 Mar 2014 13:55
Item ID:16007
Owner Only: item control page

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