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Internalization of interleukin 1 (IL 1) correlates with IL 1-induced IL 2 receptor expression and IL 2 secretion of EL4 thymoma cells

Von Hoegen, I. and Falk, Werner and Kojouharoff, G. and Krammer, P. H. (1989) Internalization of interleukin 1 (IL 1) correlates with IL 1-induced IL 2 receptor expression and IL 2 secretion of EL4 thymoma cells. European journal of immunology 19 (2), pp. 329-334.

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Abstract

The cytokine interleukin 1 (IL 1) plays an important role in the induction of IL 2 secretion and high-affinity IL 2 receptor (IL 2R) expression by T cells. The events that follow binding of IL 1 to IL 1R, however, are still unknown. In this study we describe two variants of the murine thymoma EL4 (5D3 and D6/76) that express comparable numbers of cell surface IL 1 receptors and bind IL 1 with the ...

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Item Type:Article
Date:1989
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
2522880PubMed ID
10.1002/eji.1830190217DOI
Classification:
NotationType
AnimalsMESH
Cell LineMESH
Clone Cells/metabolismMESH
Cross-Linking ReagentsMESH
Interleukin-1/physiologyMESH
Interleukin-2/metabolismMESH
Iodine RadioisotopesMESH
MiceMESH
RNA, Messenger/biosynthesisMESH
Receptors, Immunologic/analysisMESH
Receptors, Interleukin-1MESH
Receptors, Interleukin-2/biosynthesisMESH
Thymoma/secretionMESH
Thymus Neoplasms/secretionMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:08 Sep 2010 05:25
Last Modified:13 Mar 2014 14:00
Item ID:16008
Owner Only: item control page

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