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3H-spiroperidol binding to human peripheral mononuclear cells: methodological aspects.

Wodarz, Norbert and Fritze, J. and Kornhuber, J. and Riederer, P. (1992) 3H-spiroperidol binding to human peripheral mononuclear cells: methodological aspects. Biological psychiatry 31 (3), pp. 291-303.

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Abstract

3H-spiroperidol binding to lymphocytes has been proposed as a vulnerability marker for schizophrenia. However, the biological significance and even existence of this "binding site" are still in controversy. Therefore, the present study reevaluated methodological details using a filtration binding assay. The results indicated that some well-known, but obviously uncontrolled pitfalls might ...

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Item Type:Article
Date:1992
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
1532133PubMed ID
Classification:
NotationType
AdultMESH
Binding, Competitive/physiologyMESH
HumansMESH
Lymphocytes/metabolismMESH
MaleMESH
Receptors, Dopamine/physiologyMESH
Receptors, Dopamine D2MESH
Reference ValuesMESH
Schizophrenia/physiopathologyMESH
Schizophrenic PsychologyMESH
Spiperone/pharmacokineticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Unknown
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:27 Aug 2010 12:23
Last Modified:13 Mar 2014 13:59
Item ID:16326
Owner Only: item control page
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